Skin-melanocytic tumor Spitz nevus

Benign tumor of spindled and epithelioid melanocytes
.Epidemiology
Usually occurs before puberty, but 2/3 were age 20+ years.

• Sites
• Trunk most common; also lower extremities, head and neck
• Tongue lesions may have pseudoepithelio matous hyperplasia and resemble malignancy.
  
  

Small, symmetrical, pink-tan lesion

Micro description

• Symmetric with sharp lateral borders, usually compound nevus with prominent intraepidermal component
• 5% are junctional, 20% are dermal
• Composed of spindled and epithelioid cells
• Spindle cells may be arranged in fascicles in dermal papillae, are perpendicular to epidermis, cigar-shaped with large nuclei, have prominent nucleoli
• Epithelioid cells are dispersed individually, polygonal with abundant eosinophilic cytoplasm, distinct cell borders, large nuclei and prominent nucleoli, have variable mitotic figures, occasional multinucleation and often marked atypia, although most cells appear benign
• Cell maturation occurs in deep portion of tumor