Cervix humanpapilloma virus - HPV

• Classified as member of the family Papillomaviridae. 
• 100 HPV have been characterized, >40 identified in the genital tract.
• Low oncogenic risk (associated with genital condyloma and low grade SIL):
  • 6, 11, 42, 43, 44, 53
• High oncogenic risk (associated with high grade SIL and invasive carcinoma):
• 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66.   
• Is transmitted directly skin to skin or mucosa to mucosa.High-risk human papillomavirus (HR-HPV) prevalence correlates with cervical cancer incidence.